Patients who are allergic to dextromethorphan or any other ingredient in the suspensions could experience rash, or in extreme cases, an anaphylactic allergic reaction. There have been reports of abuse of dextromethorphan containing cold products, especially in combination with opioid products.
This is thought to be due to its potential to increase the tolerance threshold of opioids. At higher than recommended doses, dextromethorphan can produce serotonergic side effects similar to serotonin syndrome, a condition in which the body has too much free serotonin. Symptoms of this condition include confusion, excitement, restlessness, irritability, nausea, and vomiting. Delsym and Robitussin should only be used according to the directions on the package labeling and at the advice of your healthcare provider.
Delsym and Robitussin have the same profile of drug interactions given their same active ingredient. These drugs should be avoided when possible in patients taking monoamine oxidase inhibitors MAOIs.
MAOIs such as selegiline and linezolid may increase the likelihood of serotonin syndrome when used with drugs that have serotonergic activity, such as dextromethorphan products.
Memantine, a drug used in patients with dementia and Alzheimers, is an NMDA antagonist like dextromethorphan. Concurrent use of these medications could result in symptoms such as agitation and dizziness. Patients with dementia and Alzheimers may already have a tendency towards these symptoms, and drug combinations that could worsen these symptoms should be avoided. The following list is not intended to be a complete list of drug interactions. It is best to consult your doctor or pharmacist for a complete list.
Delsym and Robitussin are not indicated in the treatment of chronic cough. If you have a cough that lasts for more than one week or any cough that is accompanied by fever, rash, or nausea and vomiting, these could be signs of a more serious condition.
You should consult a healthcare professional immediately. Delsym and Robitussin do not contain an expectorant, a medication intended to break up phlegm and mucus to allow them to clear the airways. If your cough contains an excessive amount of these substances, you should consult your healthcare provider. An expectorant, such as Mucinex guaifenesin , or other medications may be warranted.
Dextromethorphan has been linked to fatal overdoses in children. The FDA recommends that dextromethorphan, along with many other common cold remedies, not be used in children under the age of six. There are no well-controlled studies establishing safety in pregnant women, which has led the FDA to classify Delsym and Robitussin as pregnancy category C.
Mixing substances is never a good idea, but the following make for a particularly risky combo with DXM:. They include:. People can develop a substance use disorder, including addiction, around DXM. Users can develop a tolerance as well as a psychological and physical dependence to DXM. Taking more than the directed dose of DXM — or any medication for that matter — comes with risks.
Just be sure to tell them about specific symptoms so they can send the appropriate response. Have them bend their top knee inward if they can for added support. This position will keep their airways open in case they begin to vomit. In high doses, it can have serious and lasting effects, including dependence. Adrienne Santos-Longhurst is a freelance writer and author who has written extensively on all things health and lifestyle for more than a decade. Robitussin, along with many other cough-suppressant products, contain an ingredient known as DXM.
This can have dangerous interactions and side…. You may be worried about nasal spray addiction if you find yourself repeatedly reaching for your decongestant. Could it be rebound congestion instead? PCP has earned itself quite the reputation, but can it really make people lift cars? We break down the facts.
Concerned about meth withdrawal? In the last 18 months telemedicine has been used for much more than simple check-ins with the primary care physician, it's now being used to help with…. Conclusions: Psilocybin and DXM produced similar profiles of subjective experiences, with psilocybin producing relatively greater visual, mystical-type, insightful, and musical experiences, and DXM producing greater disembodiment.
Abstract Rationale: Although psilocybin and dextromethorphan DXM are hallucinogens, they have different receptor mechanisms of action and have not been directly compared.
Substances Hallucinogens Psilocybin Dextromethorphan. Normal doses of DXM medications depend on your condition and doctor recommendations. For an average adult, DXM dosage is typically between 15 mg and 30 mg three or four times a day as needed for a cough.
By comparison, people who abuse dextromethorphan take between mg and mg in one dose. People who are addicted to DXM have been known to consume as many as 3 or 4 bottles of cough syrup per day. When DXM became a popular substance of abuse in the mids, few local or state governments banned it. The federal government only released label requirements that made usage and safe doses clear. Some states passed age limits on who could buy medications containing DXM, while other states imposed limits on how many DXM-containing medications you could buy at once.
When you take dextromethorphan in large quantities it can come with uncomfortable, dangerous, and serious side effects like:. Studies show people who abuse DXM may also have problems with short and long-term memory, attention, and confusing thoughts after taking this medication in high doses. The dangers of dextromethorphan abuse increase when you take it with prescription drugs , alcohol , marijuana , or illegal drugs.
People who abuse dextromethorphan report dose-dependent plateaus. Plateau 2: mg to mg of DXM can bring about exaggerated auditory or visual sensations, psychedelic effects, feeling dizzy or imbalanced, and closed-eye hallucinations.
Plateau 3: mg to 1, mg can cause visual and auditory hallucinations or disturbances, altered consciousness, delayed reaction times, mania, panic and paranoia, and partial dissociation from reality.
0コメント