Alcohol binds to the VR1 heat receptors in your throat and mouth. Your heat receptors are then triggered by your own body temperature All liquors whiskey, tequila, rum, vodka, etc. The higher the alcohol content, the more it burns. When you drink whiskey, the liquor affects delicate tissue lining in your throat and mouth. This tissue has nerve cells that serve an important purpose: alerting your brain when you drink something too hot that can hurt you.
These nerve cells cause the burning sensation in order stop you from drinking what they sense to be dangerously hot. These cells are called vanilloid receptor-1 VR1 which are tuned to react to the acidity and temperature of food by stimulating neurons to send pain sensations to your brain. But unlike spicy compounds like capsaicin, which simply make the VR1 cells think something is hot temperature-wise, the ethanol alcohol bonds with the VR1 receptors and lowers their heat threshold.
While the VR1 receptors may normally react to temperatures above degrees Fahrenheit , for example, bonding with ethanol can lower the response temperature to just 93 degrees Fahrenheit.
The receptors are then triggered by your own body temperature Your brain interprets these signals as a fiery drink. The exact reason the nerve cells are activated in the first place?
Alcohol effectively pulls water from the cells in your throat and mouth. When these cells dry out, they send stress signals that are interpreted as a burning sensation.
That said, these signals can be reduced a bit by drinking whiskey on the rocks adding ice or whiskey stones , but the alcohol will still trigger the nerve cell response. This will make you feel warm and is the same reason why highly intoxicated people will look flushed. These range from relatively rapid changes that take place in the throat after drinking whiskey to gradual changes that take place over years and even decades.
Whiskey is one of the strongest alcoholic drinks. Straight whiskey is approximately 40 percent alcohol compared about 5 to 7 percent in beer. This means the throat is exposed to a higher concentration of alcohol per standard drink.
When whiskey reaches the throat, it often causes a burning or stinging sensation. This occurs because the concentrated alcohol irritates the lining -- or mucosa -- of the throat causing a pain response in the nerves.
Alcohol also acts as a solvent, washing away the protective mucus that lines the throat and causing a drying effect. This can lead to temporary throat dryness and soreness, and possibly a raspy or hoarse voice.
This damage sometimes progresses to cancer. Moderate to heavy drinking increases the risk for all of these cancers, with the highest risk among those who drink the most. Wine, too, though that burn is lost in the general sauce of acidity , tannin , fruit, swirling, etc. Next time you take a sip of Cabernet, notice the subtle warmth that starts to bloom just as you begin to detect notes of blackcurrant, bulky tannins, and possible overpricing.
With Scotch , bourbon , and mezcal —really with any well-made spirit or wine—it tends to be highly complimentary. Wherefore the burn? You likely already have everything you need for most of these remedies in your home. Drinking can also cause electrolyte imbalances from increased urination.
Consuming foods or drinks that contain sodium, potassium, and other essential minerals may also help replenish these electrolytes. Nutrient-dense, whole foods , like dark leafy greens, avocados, and broccoli are the best source of electrolytes, but if your hangover is making it hard to eat solid foods, you can also try consuming a low-sugar sports drink, electrolyte supplements, or soup broth.
Getting plenty of rest gives your throat and vocal cords the opportunity to heal. If you were up late the night before, you may have gotten fewer hours of sleep than usual and sleep deprivation may be contributing to your fatigue.
Many people find gargling saltwater helps them soothe a sore throat. To make a saltwater rinse, try mixing between one-quarter and half a teaspoon of salt with 8 ounces of warm water. Take a sip of the water and gargle the water in the back of your throat for about 30 seconds. Repeat as needed. Breathing in moisture from steamy air may help reduce irritation and pain in your throat.
You can also try filling a sink with hot water and covering your head with a towel as you breathe in the warm air. Sucking on lozenges, candies, or cough drops can stimulate saliva production that helps moisturize your throat. Many OTC lozenges also contain ingredients such as hexylresorcinol , which have been found to provide relief for sore throats.
Many people find warm tea helps soothe their irritated throat.
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